DRUG	SUPPLIED	DOSE	COMMENTS
DICLOFENAC (Paeds) (Voltaren, Voltaren Ophta) Mechanism of action: Non-steroidal anti-inflammatory drug (NSAID) Ref: 44, 107, 159, 506, 507 Hashkes PJ, Laxer RM. Medical treatment of juvenile idiopathic arthritis. JAMA. 2005;294(13):1671-1684. Petty RE, Laxer RM, Lindsley CB, Wedderburn LR. Textbook of Pediatric Rheumatology. 7th ed. Elsevier; 2016. Last update: 2021-08-01	suppository: 12.5 mg, 25 mg (made locally for BCCH) & 50 mg (commercially available) eye drops: 0.1% multidose bottle (5mL)	Children: Rectal: 0.5 - 1 mg/kg/dose (round to nearest 12.5 mg) PR Q812H (Max: 50 mg/dose) Maximum: 100 mg/24 hours Adults: Ophthalmic: one drop 4 times daily (44)	May increase serum levels of digoxin, methotrexate and lithium. May decrease the antiplatelet effects of ASA. Note: concomitant use of methotrexate and NSAID is a standard of care for treating JIA If suppositories are to be split in half, the splitting should be done lengthwise. Standard Prescription: diclofenac suppository__mg PR Q__H (__mg/kg/dose) diclofenac eye drops: Instill__drop(s) to __eye(s)__(frequency)