| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| DIPHENHYDRAMINE (Paeds) (Benadryl) Mechanism of action: Antihistamine Ref: 44, 112, 634 Last update: 2022-06-18 |
capsules: 25 mg, 50 mg chewable tablets: 12.5 mg liquid: 2.5 mg/mL injection: 50 mg/mL (1 mL), 50 mg/mL (PLS) |
Children: 0.5-1.25 mg/kg/dose PO/IV/IM Q6H PRN Maximum: 50 mg/dose; 300 mg/24 hr Adults: 25-50 mg/dose PO/IV/IM Q6H PRN Maximum: 100 mg/dose; 400 mg/24 hr Adjunct to epinephrine for anaphylaxis: 1 mg/kg/dose IM/IV Q4-6H PRN for cutaneous manifestations. Max: 50 mg/dose |
Potentiates side effects of anticholinergics and other CNS depressants. Adverse effects: sedation, drowsiness, dry mouth, blurred vision, gastrointestinal distress, rare paradoxical excitation. Caution in patients with asthma or narrow-angle glaucoma. Avoid subcutaneous or intradermal injections due to irritating effects. Standard Prescription: diphenhydramine__mg PO/IV/IM Q__H (__mg/kg/24hr) |