DRUG SUPPLIED DOSE COMMENTS
DOCUSATE (Paeds)
(Colace)

Mechanism of action:

Stool softener



Ref: 4


Last update: 2019-01-23
capsules: 100 mg
drops: 10 mg/mL
Children:
1.25-5 mg/kg/dose PO once daily to QID (up to 5 mg/kg/day)

Usual Dose by Age:
3-6 yr: 20-60 mg
6-12 yr: 40-100 mg
>12 yr and Adult: 100-200 mg
PO: Requires 1-3 days to effectively soften stools. Ensure adequate fluid intake.

PR: Can be given rectally as enema to older children (add 50-100 mg of oral solution to enema fluid).

Do not administer concurrently with mineral oil as increased absorption of mineral oil may occur (docusate is a surfactant).

Oral liquid is BITTER. Diluting in milk, formula, or juice may help disguise bad taste.

Standard Prescription:

docusate__mg PO__(frequency) (__mg/kg/24hr) or (__mg/24hr)