DRUG SUPPLIED DOSE COMMENTS
ETHACRYNIC ACID (Paeds)
(Edecrin)

Mechanism of action:

loop diuretic



Ref: 44


Last update: 2021-02-20
Tablet: 25 mg
injection: 50 mg/vial
Children:
PO:
  • 1 mg/kg/dose PO once daily
  • Increase at intervals of 2 to 3 days to max of 3 mg/kg/day.
IV:
  • 0.5 to 1 mg/kg/dose IV
  • May repeat every 8 to 12 hours if necessary
  • Maximum 100 mg/dose.
  • Maximum rate of injection is 10 mg over 1 min.; too rapid injection may cause temporary or permanent deafness.
  • Monitor serum electrolytes and fluid balance
  • Loop diuretic for diuresis of patients refractory to conventional diuretic therapy or allergic to sulfonamides


Standard Prescription:

ethacrynic acid__mg PO Q__H(__mg/kg/day)
ethacrynic acid__mg IV Q__H (__mg/kg/dose)