DRUG SUPPLIED DOSE COMMENTS
FLUDROCORTISONE (Paeds)
(Florinef)

Mechanism of action:

Synthetic mineralocorticoid



Ref: 44


Last update: 2021-12-07		 tablet: 0.1 mg Infants and children:
Adrenal Insufficiency: 0.05-0.1 mg/dose PO once or twice daily (Daily dose 0.05-0.2 mg)
Congenital adrenal hyperplasia (salt losers): 0.05-0.1 mg/dose PO once or twice daily (Usual daily dose 0.05-0.2 mg/day; however, doses as high as 0.3 mg per day may be required) .

Adults:
0.05-0.2 mg/dose PO daily
Tablets may be crushed and placed in 1 tsp water or soft food (ex. yogurt, applesauce).

Titrate dose to maintain plasma renin activity at normal levels.

Monitor BP, serum electrolytes and glucose. Adjust dose if hypertension, hypernatremia or hypokalemia develop.

Has primarily mineralocorticoid activity.

Refer to Corticosteroid Equivalency Table in Supplementary Materials.

Contraindicated in systemic fungal infections.

Use with caution in heart failure, hypertension, edema, diabetes, renal or liver dysfunction, GI disorders.


Standard Prescription:

fludrocortisone__mg PO [frequency]