| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| PEG 3350 LAXATIVE (Paeds) (polyethylene glycol, Lax-a-day, Miralax, Pegalax) Mechanism of action: Osmotic agent which draws water into the stool Ref: 78, 104, 423 Last update: 2019-08-13 |
Powder Standardized dose package sizes: 5g, 8g, 12.5g, 17g (commercially available as Lax-a-day) 20g |
Children: Constipation: 0.4-0.8 g/kg/dose PO daily (Max 34 g/day) Fecal disimpaction: 1-1.5 g/kg/dose PO daily x 3-6 days (Max 100 g/day) Adults: Usual dose: 17 g po daily Doses will be standardized as per PT&N Dose Standardization Policy unless "do not round dose" is written |
Dissolve dose in 250 mL of water, juice or milk. Daily doses can also be divided BID. PEG 3350 is an osmotic laxative that increases the water content of stools. It is minimally absorbed in the GI tract and carries no risk of electrolyte imbalances. Onset of action: 2 to 4 days. Most common side effects: abdominal pain, bloating, flatulence and loose stools. For home use, volume measures may be easier; 17 grams is approximately equivalent to a heaping tablespoon, or refer to package directions. Standard Prescription: PEG 3350 __g PO __(frequency) |