DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
LINEZOLID (Paeds) (Zyvoxam) Mechanism of action: Oxazolidinone antibiotic: inhibits bacterial protein synthesis to prevent formation of 70S initiation complex Ref: 6, 44, 211 Last update: 2022-07-05 |
injection: 2 mg/mL (300 mL) tablet: 600 mg |
Children < 12 years: 10 mg/kg/dose PO/IV Q8H > 12 years old and Adults: 10 mg/kg/dose PO/IV Q12H Maximum: 600 mg/dose |
Bioavailability 100% Reversible, nonselective MAO inhibitor. Check for drug interactions Thrombocytopenia, anemia, leucopenia, pancytopenia reported with duration of therapy > 10 days. Monitoring CBC weekly during long-term therapy is recommended. Standard Prescription: linezolid__mg IV/PO Q__H (__mg/kg/24hr) |