| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| MEROPENEM (Paeds) (Merrem) Mechanism of action: Carbapenem antibiotic Ref: 6, 44, 213, 627 Last update: 2022-07-06 |
Injection: 500 mg vial; 1 g vial |
Children: Urinary Tract Infection: 10 mg/kg/dose IV Q8H Moderate to Severe Infections: 20 mg/kg/dose IV Q8H Febrile Neutropenia: 20 mg/kg/dose IV Q8H. Maximum: 1000mg/dose Cystic Fibrosis: 40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose Meningitis: 40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose |
Doses require adjustment if creatinine clearance is < 50 mL/min. Less nausea and vomiting, decreased risk of seizures compared to imipenem. Standard Prescription: meropenem__mg IV Q__H (__mg/kg/24hr) |