DRUG	SUPPLIED	DOSE	COMMENTS
METOLAZONE (Paeds) (Zaroxolyn) Mechanism of action: Thiazide diuretic Ref: 44, 192 Last update: 2022-07-06	tablet: 2.5 mg suspension (BCCH): 1 mg/mL	Children: 0.1-0.2 mg/kg/dose PO once daily-BID. Maximum: 10 mg BID. Adult: 5-20 mg PO once daily	Concurrent administration of metolazone and furosemide significantly potentiates the diuretic effects of furosemide. More effective than thiazide diuretics in impaired renal function; may be effective in GFRs as low as 20 mL/min. Onset of action 1 hour. Standard Prescription: metolazone__mg PO__(frequency) (__mg/kg/24hr)