DRUG SUPPLIED DOSE COMMENTS
METOPROLOL (Paeds)
(Betaloc)

Mechanism of action:

Beta-1 selective beta-adrenegic blocker



Ref: 29, 65 , 192, 193


Last update: 2019-06-29
tablet: 50 mg, 100 mg
liquid (BCCH): 5 mg/mL, 10 mg/mL
injection: 5 mg/mL
Hypertension:
Initial: 0.5-1 mg/kg/dose PO BID
Max dose: 6 mg/kg/24 hr

CHF/Cardiomyopathy:
Initial: 0.1 -0.2 mg/kg/dose PO BID. Increase as tolerated to maintenance dose of 0.25-1mg/kg/dose PO BID

Adults:
Hypertension: 12.5-50 mg PO daily (Max dose 450 mg/24hr)
CHF: initial dose 12.5-25 mg PO Daily to a target of 200 mg/day (S/R product-not stocked at BCCH)
Allow at least 3 days between dose adjustments when treating hypertension.

Allow 1-2 weeks between dose adjustments when treating cardiomyopathy/CHF due to short-term negative inotropic effects.

Use with caution in reactive airway disease.


Standard Prescription:

metoprolol__mg PO Q__H (__mg/kg/24hr)