DRUG SUPPLIED DOSE COMMENTS
NYSTATIN (Paeds)


Mechanism of action:

Antifungal



Ref: 6, 44



Last update: 2022-12-19		 suspension: 100,000 units/mL

topical ointment and cream: 100,000 units/g

vaginal cream: 25,000 units/g		 Suspension:
Swish (30-60 sec) and swallow or apply to recesses of the mouth:

Infants:  200,000-400,000 U/dose (2 to 4 mL/dose) PO QID
Children and Adults:  400,000-600,000 U/dose (4 to 6 mL/dose) PO QID

Topical Ointment and Cream:
Apply liberally to affected area BID-QID.

Vaginal Cream:
One applicator of cream vaginally once or twice daily x 14 days.		 Treat until 48-72 hour after resolution of symptoms. Usual treatment duration for oral candidiasis is 10-14 days.

Poor absorption orally.

Adverse effect: diarrhea and GI upset.

Topical cream is preferred to ointment in diaper areas.


Standard Prescription:

nystatin__units PO swish and swallow__(frequency)

nystatin topical ointment apply to affected area__(frequency)

nystatin vaginal cream: apply one applicatorful__(frequency) x__days