DRUG SUPPLIED DOSE COMMENTS
PENICILLIN G SODIUM (Paeds)


Mechanism of action:

Beta-lactam antibiotic.



Ref: 5, 6, 44, 229



Last update: 2022-08-25		 Injection: 1 mu/vial, 5 mu/vial, 10 mu/vial
Mild to Moderate Infections:
25,000-63,000 units/kg/dose IV Q6H

Severe Infections:
42,000-67,000 units/kg/dose IV Q4H

Meningitis:
67,000 units/kg/dose IV Q4H

Congenital syphilis: (>= 1 month)
50,000 units/kg/dose IV Q4-6H
(Please consult ID)

Maximum: 4 million units/dose
 BCCH uses penicillin G sodium which provides 1.68 mEq Na + per 1,000,000 U.

Dose adjustment recommended in renal dysfunction.

Consult infectious disease for all cases of congenital syphilis.


Standard Prescription:

penicillin G __units IM/IV Q__H (__units/kg/24 hr