DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
PRIMAQUINE PHOSPHATE (Paeds) Mechanism of action: Anti-malarial. Ref: 6, 22, 44, 201 Last update: 2022-09-09 |
tablet: 26.3 mg (= 15 mg primaquine base) | Doses expressed in terms of mg primaquine phosphate Treatment of Malaria: 0.88 mg/kg/dose PO daily x 14 days. 30-59 kg: 26.3 mg (1 tablet) PO daily x 14 days > 60 kg: 52.6 mg (2 tablets) PO daily x 14 days Maximum dose: 52.6 mg primaquine phosphate/dose |
Used in combination with appropriate acute antimalarial treatment of P. vivax and P. ovale malaria for "radical cure" as it has activity against liver stage; not used as a single agent. May cause massive hemolysis in patients with G6PD deficiency; Prior to use, G6PD testing needed to confirm normal activity. Give with food to mask bitter taste. Standard Prescription: primaquine __mg base PO Q__H (__mg base/kg/24 hr) |