DRUG SUPPLIED DOSE COMMENTS
PRIMAQUINE PHOSPHATE (Paeds)


Mechanism of action:

Anti-malarial.


Ref: 6, 22, 44, 201



Last update: 2022-09-09
tablet: 26.3 mg (= 15 mg primaquine base) Doses expressed in terms of mg primaquine phosphate

Treatment of Malaria:
0.88 mg/kg/dose PO daily x 14 days.  
30-59 kg: 26.3 mg (1 tablet) PO daily x 14 days
> 60 kg: 52.6 mg (2 tablets) PO daily x 14 days

Maximum dose: 52.6 mg primaquine phosphate/dose

Used in combination with appropriate acute antimalarial treatment of P. vivax and P. ovale malaria for "radical cure" as it has activity against liver stage; not used as a single agent.

May cause massive hemolysis in patients with G6PD deficiency; Prior to use, G6PD testing needed to confirm normal activity.

Give with food to mask bitter taste.


Standard Prescription:

primaquine __mg base PO Q__H (__mg base/kg/24 hr)