DRUG SUPPLIED DOSE COMMENTS
ZOPICLONE (Paeds)
(Imovane)

Mechanism of action:

Hypnotic


Ref: 4, 44, 83



Last update: 2021-08-02
tablet: 5 mg, 7.5 mg

3.75 mg (not stocked at BCCH)
 Adolescents & Adults:
3.75 mg PO HS
Maximum 7.5 mg/24hrs		 Increasing dose above 7.5 mg does not increase efficacy.

Not well studied in children/adolescents.

Common adverse effects: bitter/metallic taste, dry mouth, palpitations, tremor, rash, chills, sweating, agitation, nightmares, confusion, incoordination.

Rarely may cause hallucinations and behavioural disturbance.

Instruct patients to wait at least 12 hours after dose before driving or engaging in activities requiring full mental alertness.

Caution in respiratory impairment, liver dysfunction and depression.

Dependence/abuse potential appears to be lower compared to benzodiazepines.

Not interchangeable with eszopiclone (S-isomer of zopiclone).


Standard Prescription:

zopiclone__mg PO HS