DRUG SUPPLIED DOSE COMMENTS
SCOPOLAMINE HYDROBROMIDE (Paeds)
(Hyoscine)

Mechanism of action:

Anticholinergic agent.



Ref: 24, 44, 472, 473



Last update: 2019-08-26
injection: 0.4 mg/mL, 0.6 mg/mL.
patch: 1.5 mg (non-formulary).
Pre-op and antiemetic:
Children: 6 mcg/kg/dose SC/IM/IV/PO (max 0.3 mg/dose).
May repeat every 6-8 H.

Excessive drooling:
3-11 yrs: 1/2 patch applied transdermally Q72H.
>=12 yrs: 1 patch applied transdermally Q72H.
Contraindicated in patients with glaucoma, urinary or GI obstruction.

Well absorbed orally; peak concentration achieved in one hour.

Injectable form may be given orally.

Anticholinergic toxicities; see atropine comments. Case reports of toxicity with scopolamine patch. Monitor for hyperthermia, decreased vision, delirium. Use lowest effective dose.

Do not cut scopolamine patches. If a half patch is required, place Tegaderm or similar impermeable material on the skin underneath the patch, covering half the skin under the patch.


Standard Prescription:

scopolamine __mcg SC/IM/IV/PO Q__H {PRN} (__mcg/kg/dose)