DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
SCOPOLAMINE HYDROBROMIDE (Paeds) (Hyoscine) Mechanism of action: Anticholinergic agent. Ref: 24, 44, 472, 473 Last update: 2019-08-26 |
injection: 0.4 mg/mL, 0.6 mg/mL. patch: 1.5 mg (non-formulary). |
Pre-op and antiemetic: Children: 6 mcg/kg/dose SC/IM/IV/PO (max 0.3 mg/dose). May repeat every 6-8 H. Excessive drooling: 3-11 yrs: 1/2 patch applied transdermally Q72H. >=12 yrs: 1 patch applied transdermally Q72H. |
Contraindicated in patients with glaucoma, urinary or GI obstruction. Well absorbed orally; peak concentration achieved in one hour. Injectable form may be given orally. Anticholinergic toxicities; see atropine comments. Case reports of toxicity with scopolamine patch. Monitor for hyperthermia, decreased vision, delirium. Use lowest effective dose. Do not cut scopolamine patches. If a half patch is required, place Tegaderm or similar impermeable material on the skin underneath the patch, covering half the skin under the patch. Standard Prescription: scopolamine __mcg SC/IM/IV/PO Q__H {PRN} (__mcg/kg/dose) |