DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
SODIUM BICARBONATE (Paeds) (NaHCO3; Sodamint; baking soda) Mechanism of action: Electrolyte supplement. Ref: 32, 44 Last update: 2023-05-13 |
tablet: 325 mg (3.9 mmol) 500 mg (6 mmol). injection: 8.4% 10 mmol/10 mL PFS, 8.4% 50 mmol/50 mL PFS, 4.2% 5 mmol/10 mL PFS. injection: 8.4% 50 mmol/50 mL vial. 1 tsp (5 mL) provides 4800 mg of sodium bicarbonate = 57 mmol sodium and 57 mmol bicarbonate |
Metabolic Acidosis Intermittent Infusion: HCO3 (mmol) = 0.3 x weight (kg) x base deficit (mmol/L). Administer 1/2 the calculated dose IV over 30 - 60 min and the remaining 1/2 over the next 24 hrs (usual dose is 0.5-2 mmol/kg/hr). Acidosis of chronic renal failure: Children: 1-3 mmol/kg/day PO in divided doses Adults: 20-36 mmol/day PO in divided doses. Renal tubular acidosis (Distal): Children: 2-3 mmol/kg/day PO in divided doses. Adults: 0.5-2 mmol/kg/day PO given in 4 to 5 divided doses. Renal tubular acidosis (Proximal): Children and adults: 5-10 mmol/kg/day PO in divided doses, and titrate to maintain serum bicarbonate in the normal range. Urinary Alkalinizer: 0.25-3.3 mmol/kg/dose PO/IV Q6-8H; titrate to desired urinary pH. Cystic Fibrosis: 325-1300 mg (using 325 mg tablets) per dose PO before meals/snacks with pancreatic enzymes. |
Routine use in cardiac arrest is not recommended. For metabolic acidosis use only after adequate alveolar ventilation is established. Use 8.4% concentration for children, 4.2% concentration for neonates and infants. May be used as an adjuvant to pancreatic enzymes in CF. 1 mmol = 1 mEq Na + and 1 mEq HCO3. For blocked enteral feeding tubes, use 4 mL of injectable form to dissolve pancreatic enzymes. See PHSA SHOP for Guidelines for Clearing a Blocked Enteral Feeding Tube. Standard Prescription: sodium bicarbonate __mEq/kg/hr IV infusion sodium bicarbonate __tabs PO ___(frequency) |