| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| VITAMIN K (Paeds) (Phytonadione) Mechanism of action: Vitamin supplement Ref: 16, 44, 58, 260 Last update: 2019-09-01 |
injection (Phytonadione, K1): 1 mg/0.5 mL, 10 mg/mL | Neonatal Hemorrhagic Disease: Prophylaxis: IM (Route of choice) 0.5-1 mg/dose IM x 1 within 6 hr after birth PO (If parents refuse IM route) 2 mg PO x 3 doses (at birth, 2-4 weeks of age and at 6-8 weeks of age). Treatment: 1-2 mg/24 hr IM/SC/IV Vitamin K Deficiency due to Malabsorption or decreased synthesis of Vitamin K: Infants and Children: 1-5 mg/dose /IV/SC x 1 or 2.5-5 mg/24 hr PO daily May repeat dose depending on severity of deficiency and response to treatment. Adults: 2.5-25 mg/24 hr PO/IV/SCVitamin K supplementation in Cystic Fibrosis: 1-5 mg/dose PO once daily. |
Injectable form may be given orally. Use IV/ route only when other routes of administration are not feasible (IV/ may cause flushing, dizziness, hypotension, anaphylaxis). For use as warfarin antidote; see Warfarin section in Protocol for Anticoagulant and Thrombolytic Therapy in References and Supplementary. Standard Prescription: vitamin K__mg IM/SC/IV{PO} X 1 dose vitamin K__mg IM/SC/IV{PO}__(frequency) |