DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
SOTALOL (Paeds) (Sotacor) Mechanism of action: Class III antiarrhythmic agent (prolongs action potential) with minor class II (non-selective beta-blocking) effects. Ref: 44, 52, 242 Last update: 2022-09-11 |
Tablet: 80 mg, 160 mg Suspension (BCCH): 5 mg/mL |
< 2 yr : 30 mg/m2/dose x age related factor PO Q8H refer to nomogram for age related factor (see link in comments) Cardiology Consult required Usual starting dose: 1 mg/kg/dose PO Q12H Increment: 1-2 mg/kg/24 hr every 3 days Maximum: 2.7 mg/kg/dose PO Q8H (8 mg/kg/24 hours) OR Initial: 30 mg/m2/dose PO Q8H Max: 60 mg/m2/dose PO Q8H Adults: 80 mg PO BID to max 320 mg/24hr |
Class III antiarrhythmic agent (prolongs action potential) with minor class II (non-selective beta-blocking) effects Reduce dose in renal impairment. Use caution in reactive airway disease. May cause pro-arrhythmic effects e.g. prolongation of QT and risk of torsade, AV block. Dosing for < 2 years old found on UpToDate at: http://www.uptodate.com/contents/images/DRUG/78350/Sotalol.jpg?title=Age+nomogram. Standard Prescription: sotalol__mg PO Q__H (__mg/kg/24hour) |