DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
ICATIBANT (Paeds) (Firazyr) Mechanism of action: Icatibant acts as a bradykinin inhibitor by blocking the binding of native bradykinin to the bradykinin B2 receptor Ref: 142, 293 Last update: 2019-04-03 |
Single Dose Pre-filled Syringe (PFS): 30 mg/3 mL |
Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) type I/II acute, episodic attack Children (>=2 years) and adolescents: 0.4 mg/kg/dose SC x 1 dose Maximum: 30 mg/dose Note: in adults doses may be repeated after 6 hrs, up to a maximum of 3 doses total in 24hr |
For slow subcutaneous injection in the abdominal region Injection site reactions are common (eg. erythema, swelling, warm sensation, burning, itching and/or cutaneous pain) Standard Prescription: Icatibant __mg SC one dose (__mg/kg/dose) |