| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| DAPTOMYCIN (Paeds) (Cubicin) Mechanism of action: Lipopeptide antibiotic, disrupting bacterial cell membrane function Ref: 6, 44, 619 Last update: 2022-06-17 |
Injection: 500 mg vial | MRSA Bacteremia and Osteomyelitis: <=6 years: 12 mg/kg/dose IV Q24H 7 - 11 years: 9 mg/kg/dose IV Q24H 12 - 17 years: 7 mg/kg/dose IV Q24H |
Restricted to treatment of severe infections caused by resistant Gram-positive organisms, where other agents cannot be used. Monitor creatine phosphokinase at baseline and once weekly during therapy. Standard Prescription: daptomycin __ mg IV Q _ H (__ mg/kg/24hr) |