DRUG SUPPLIED DOSE COMMENTS
CETIRIZINE (Paeds)
(Reactine)

Mechanism of action:

Second generation selective antagonist of the histamine H1 receptor.


Ref: 44, 195, 196, 499, 501


Last update: 2022-06-16		 tablet: 5 mg, 10 mg

chewable tablet: 5 mg

liquid: 1 mg/mL
Children 6-12 months:
2.5 mg PO once daily.

Children 1-5 years old:
2.5-5 mg PO once daily.

6-11 years old:  
5-10 mg PO once daily

> 12 years old:
10 mg PO once daily

 Dose may be divided BID instead of once daily.

Second generation H1-antihistamine derived from the metabolism of hydroxyzine.
 
More sedation compared to loratadine.

Onset of action: 20-60 minutes.

May be administered 30 minutes before transfusions to prevent transfusion-related reactions.


Standard Prescription:

Cetirizine __ mg PO daily