| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| CLOPIDOGREL (Paeds) (Plavix) Mechanism of action: Platelet activation inhibitor. A prodrug activated in two steps to an active metabolite that irreversibly inhibits the P2Y12 subtype of the ADP receptor, which is important in activation of platelets and eventual cross-linking by the protein fibrin Ref: 90, 141, 149, 294 Last update: 2019-08-01 |
Tablet: 75 mg, 300 mg | Pediatric: 0.2 - 1 mg/kg/dose PO once daily Adults: 75 mg PO once daily |
children less than 2 years old may require lower end of the dosage range. used alone or in combination with ASA for post cardiac stents. Use cautiously in patients with low platelets and bleeding disorders. Standard Prescription: Clopidogrel __ mg PO daily ( __ mg/kg/dose) |