DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
BASILIXIMAB (Paeds) (Simulect) Mechanism of action: Chimeric anti-interleukin-2 receptor monoclonal antibody. Ref: 32, 44 Last update: 2022-06-09 |
Injection: 20 mg/vial | Kidney Transplant Induction: Day 0 and Day 4: 12 mg/m2/dose IV. Minimum: 10 mg/dose. Maximum 20 mg/dose Give 4 hours pre-op on Day 0 May also dose by weight category: <35 kg: 10 mg IV >=35 kg: 20 mg IV |
Medications for treatment of severe hypersensitivity reactions should be available for immediate use. Patients are not usually given a second course of basiliximab for transplant induction due to the risk of severe allergic reaction/anaphylaxis, but each case must be considered on an individual basis. Day 0 = day of transplant. Standard Prescription: basiliximab __mg IV x 1 dose (__mg/m2/dose) |