DRUG SUPPLIED DOSE COMMENTS
INTRALIPID (Paeds)


Mechanism of action:

Antidote for poisoning or overdose caused by a wide array of other (non-local anesthetic) lipophilic agents




Ref: 412


Last update: 2022-04-04
Injection: 20%
Intralipid: 100% soybean oil
Lipid rescue for overdose of local anesthesia:

Bolus: 1.5 mL/kg IV over 1 minute; maybe be repeated once or twice for persistent cardiovascular collapse.

Continuous IV infusion (following bolus): 0.25 mL/kg/min.

Rate may be doubled to 0.5 mL/kg/min if blood pressure remains low.

Continue infusion for at least 10 minutes after attaining circulatory stability.

Recommended maximum: 10 mL/kg over the first 30 minutes
For more details regarding lipid rescue visit website: lipidrescue.org or consult BC Drug and Poison Centre.

For nutritional information refer to the nutrition manual.



Standard Prescription:

Bolus: __  mL IV over 1 minute (__ mL/kg)
Infusion: __ mL/min (__ mL/k/min) for __ minutes