| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| CEFOTAXIME (Paeds) (Claforan) Mechanism of action: Third-generation cephalosporin antibiotic Ref: 6, 44, 229 Last update: 2022-06-15 |
Injection: 1 g, 2 g |
Infants and Children: 35-70 mg/kg/dose IM/IV Q8H Severe Infections: 50 mg/kg/dose IM/IV Q6H . Meningitis: 75 mg/kg/dose IM/IV Q6H (300 mg/kg/24 hr IV div. Q4-Q6H). Maximum: 2000 mg IV Q4H Adults: Usual dose 1-2 g IM/IV Q6-8H. Maximum: 2 g IV Q4H |
Dosage adjustment is required in severe renal impairment. Third generation cephalosporin with similar spectrum of activity to ceftriaxone. Cefotaxime is preferred over ceftriaxone in the neonatal population (see ceftriaxone dosing monograph). Standard Prescription: cefotaxime__mg IV Q H ( mg/kg/24hr) |