DRUG | SUPPLIED | DOSE | COMMENTS |
---|---|---|---|
BUMETANIDE (Paeds) (Burinex) Mechanism of action: Loop diuretic Ref: 44, 112 Last update: 2018-12-03 |
Tablet: 1 mg, 5 mg Injection: 2 mg/4 mL (injection requires approval from Health Canada Special Access Program) |
Infants and children: 0.015 to 0.1 mg/kg/dose PO/NG/IV every 6 to 24 hrs Adults: 0.5 to 2 mg/dose PO/NG/IV every 12 to 24 hrs; Maximum 10 mg/day |
May cause hypokalemia, alkalosis, dehydration, hyperuricemia, increased calcium and magnesium excretion, nephrocalcinosis. For use in cardiac patients who are unresponsive to furosemide. Maximal diuretic effects were found to occur at doses of 0.04 mg/kg in critically ill infants. Standard Prescription: bumetanide __mg (__mg/kg/dose) (PO/NG/IV) Q__H |