DRUG SUPPLIED DOSE COMMENTS
CALCIUM GLUCONATE (Paeds)


Mechanism of action:

Calcium electrolyte replacement



Ref: 37, 44


Last update: 2021-11-13
injection: 10% (100 mg/mL) 10 mL vial

10% solution contains: 0.23 mmol elemental Ca/mL, 9.3 mg elemental Ca/mL

Hypocalcemia, Hypermagnesemia or Calcium Channel Blocker Overdose:
0.6 mL-1 mL /kg/dose  (5.6-9.3 mg elemental Ca/kg/dose [60-100 mg Ca gluconate/kg/dose]) IV push.  Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose)

Hyperkalemia
0.5 mL/kg/dose (4.6 mg elemental Ca/kg/dose [50 mg Ca gluconate/kg/dose]) IV push. Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose).  May repeat dose in 5 minutes if ECG changes persist

Hypocalcemia with seizures or tetany
1 mL/kg/dose (9.3 mg elemental Ca/kg/dose [100 mg Ca gluconate/kg/dose]) IV push, may repeat in 6 hours or continue with an infusion 18.6 mg elemental Ca/kg/day (200 mg Ca gluconate/kg/24h)
 

Continuous IV infusion:
18.6-47 mg elemental Ca/kg/24 hr
(200-500 mg Ca gluconate/kg/24 hr)
1 gram calcium gluconate = 93 mg elemental calcium (Ca) = 2.3 mmol elemental Ca.

Routine use in cardiac arrest is not recommended due to lack of survival benefit.

Calcium chloride is preferred to correct emergent hypocalcemia.

Contraindicated in patients with digoxin toxicity or hypercalcemia.

Incompatible with sodium bicarbonate, ceftriaxone, phosphate, and lipids.

Monitor for bradycardia or dysrhythmia.

Avoid extravasation as severe necrosis and tissue sloughing will occur.

Refer to ePOPS for Prevention and Management of Infiltration and Extravasation Calcium concentration should be less than 20 mg/mL for peripheral administration.

Standard Prescription:

calcium gluconate    mg IV (    mg/kg/dose) x 1 dose

calcium gluconate    mg/hr IV infusion (__mg/kg/hr)