DRUG SUPPLIED DOSE COMMENTS
CELECOXIB (Paeds)
(Celebrex)

Mechanism of action:

A COX-2 selective, non-steroidal anti-inflammatory drug (NSAID).


Ref: 44, 156


Last update: 2021-11-13
capsule: 100 mg, 200 mg

suspension (BCCH):  
10 mg/mL
 Juvenile Idiopathic Arthritis (JIA):
Children >2 years old:
10 to 25 kg: 50 mg PO BID
>25 kg: 100 mg PO BID

Adults:  
100 - 200 mg/dose PO daily or BID.
Maximum: 400 mg/24 hours

 May increase serum levels of digoxin, methotrexate and lithium. May decrease the antiplatelet effects of ASA.
Note: concomitant use of methotrexate and NSAID is a standard of care for treating JIA.

Minimal platelet effect compared to other NSAIDs.

See Health Canada warning (2006) for cardiovascular risks.


Standard Prescription:

celecoxib __mg PO__(frequency)