| DRUG | SUPPLIED | DOSE | COMMENTS |
|---|---|---|---|
| CEPHALEXIN (Paeds) (Keflex) Mechanism of action: First generation cephalosporin antibiotic Ref: 44, 614 Last update: 2022-06-16 |
Capsule: 250 mg, 500 mg Suspension: 50 mg/mL |
Children: Mild to Moderate Infections: 15 mg/kg/dose PO Q8H or Q6H. Max 4 g/day Severe Infections: 25 mg/kg/dose PO Q6H. Max 4 g/day Osteomyelitis: 37.5 mg/kg/dose PO Q6H. Max 4 g/day Cystic Fibrosis: 25-40 mg/kg/dose PO Q6H. Max 4 g/day Mild to Moderate infections: 250-500 mg/dose PO Q6H. Max 4 g/day Severe Infections: 500-1000 mg/dose PO Q6H. Max 4 g/day |
More palatable, less GI upset and higher bioavailability than PO cloxacillin. Cefazolin sensitivity does not predict susceptibility to cephalexin. Dosage adjustment required in renal impairment. Standard Prescription: cephalexin__mg PO Q__H (__mg/kg/24hr) |