DRUG SUPPLIED DOSE COMMENTS
CHLORPHENIRAMINE (Paeds)
(Chlor-Tripolon)

Mechanism of action:

First generation antihistamine, potent inverse agonist of the histamine H1 receptor



Ref: 44, 133, 500


Last update: 2022-06-16		 tablet: 4 mg
 Children 6-11 years:
2 mg PO Q4-6H (max: 12 mg/24 hr)

Children ≥12 years:
4 mg PO Q4-6H (max: 24 mg/24 hr)

 Health Canada does not recommend use in children under 6 years old.

May cause excitation in young children.

Use with caution in asthma.

May cause dose-related CNS and anticholinergic effects (sedation, dry mouth, blurred vision, urinary retention, and disturbed coordination).


Standard Prescription:

chlorpheniramine __mg PO Q   H (__mg/kg/24 hr)