DRUG SUPPLIED DOSE COMMENTS
CHOLESTYRAMINE (Paeds)
(Questran)

Mechanism of action:

Bile acid sequestrant



Ref: 1, 4, 44



Last update: 2019-01-13		 powder: each 9 g of powder contains 4 g of anhydrous resin Children: 80 mg resin/kg/dose PO TID up to 8 g/24 hr

Adults: Initial dose: 4 g resin/dose once dailyQID;
may be given up to 6 times per day to a maximum 24 g/24 hr for hypercholesterolemia or 16 g/24 hr for pruritis secondary to cholestasis
 Mix with 60-180mL of water, juice or milk before meals.

Use with caution in young children.

Due to its anion exchange properties, it may cause hyperchloremic acidosis; follow electrolytes, especially bicarbonate.

May also cause constipation,decreased absorption of fat soluble vitamins and altered absorption of other drugs. Take other drugs 1 hour before or 4-6 hours after cholestyramine.

Standard Prescription:

cholestyramine __g resin PO__(frequency) (__mg resin/kg/24hr)