EPINEPHRINE INHALED

(alternative to racemic epinephrine - not commercially available in Canada)

Standard Prescription

epinephrine 2.5 to 5 mg (2.5 to 5 ml) inhaled via nebulizer Q__H PRN for ____ doses

Dosages

Croup:
5 mL/dose (5mg/dose) via nebulizer up to Q1H

**If >= 3 doses required within 2-3 hours, contact  PICU medical staff**


Mechanism of Action

Alpha and beta adrenergic agonist

Forms Supplied

IV solution: 1 mg/mL, 30 mL vial

Epinephrine topical solution (same strength as IV solution) can be used for inhalation but BCCH will use the IV solution for inhalation as per March 2010 PTN decision.

Comments

Tachyphylaxis can occur (decreased response with repeated doses).

For upper airway obstruction (croup) to be administered by respiratory therapists (RT) or physician (MD).  Registered nurse (RN) may administer if MD present. .  If necessary, after verbal approval by MD, RN may initiate the epinephrine nebulizer prior to RT or MD arrival so as not to delay treatment.

For lower airway obstruction (bronchiolitis) RNs may administer

Patients should be assessed by MD or RT before and after administration.

See on-line procedure (SHOP) for Aerosol Therapy using nebulizer

References

51, 245

Last Edited

2022-12-20 06:59:20