ESMOLOL
(Brevibloc)Standard Prescription
esmolol__ mcg IV x 1 loading dose
esmolol__mcg/kg/min continuous IV infusion
esmolol__mcg/kg/min continuous IV infusion
Dosages
Supraventricular Tachycardia
Loading dose: 100-500 mcg/kg IV over 1 to 2 min.
Infusion rate: 50-100 mcg/kg/min and titrate by 50 -100 mcg/kg/min every 5 to 10 min until a 10% reduction in heart rate or mean arterial pressure occurs.
Post-op hypertension
Loading dose: 100 - 500 mcg/kg IV over 1 to 2 min.
Infusion rate: 50 - 150 mcg/kg/min and titrate by 50 100 mcg/kg/min every 5 to 10 min.
Maximum infusion rate: 1000 mcg/kg/min
Loading dose: 100-500 mcg/kg IV over 1 to 2 min.
Infusion rate: 50-100 mcg/kg/min and titrate by 50 -100 mcg/kg/min every 5 to 10 min until a 10% reduction in heart rate or mean arterial pressure occurs.
Post-op hypertension
Loading dose: 100 - 500 mcg/kg IV over 1 to 2 min.
Infusion rate: 50 - 150 mcg/kg/min and titrate by 50 100 mcg/kg/min every 5 to 10 min.
Maximum infusion rate: 1000 mcg/kg/min
Mechanism of Action
Class II antiarrythmic; Beta-adrenergic blocker
Forms Supplied
Injection: 10 mg/mL, 10 mL vial
Comments
For use in Critical Care areas only.
Monitor heart rate, blood pressure, ECG, respiratory rate continuously
A 10% reduction in heat rate or blood pressure signifies beta blockade
Onset of beta blockade occurs within 2 to 10 min.
Duration of action 10-30 min.
Monitor heart rate, blood pressure, ECG, respiratory rate continuously
A 10% reduction in heat rate or blood pressure signifies beta blockade
Onset of beta blockade occurs within 2 to 10 min.
Duration of action 10-30 min.
References
460, 461, 462
Last Edited
2019-01-25 07:07:16