ETHANOL 70% Lock
(Ethyl alcohol 70%)Standard Prescription
ethanol 70% for CVC lock
ethanol 70% lock for occluded CVC per protocol
ethanol 70% lock for occluded CVC per protocol
Dosages
For CVC lock:
Prescribed volume is equal to the central venous catheter (CVC) or port priming volume + extension set volume + needleless connect (cap) volume.
Maximum once daily.
For Occluded CVC:
See Child and Youth Health Policy for Management of Non-Functioning Central Venous Lines on ePOPS.
For Methanol and Ethylene Glycol poisoning, see Ethanol 99%.
Mechanism of Action
Dissolves lipid build-up caused by TPN infusions
Forms Supplied
Injection: 70% Ethanol (prepared by Pharmacy in 5 mL syringe)
Comments
For CVC lock:
- Flush CVC with normal saline to ensure patency.
- Instill prescribed volume into the CVC and needleless connector.
- Allow to dwell for prescribed time (minimum 4 hours and maximum 24 hours).
- To remove, aspirate ethanol and 1 mL of blood. Discard. Do not flush ethanol lock into patient.
- If the ethanol cannot be aspirated and the CVC appears occluded, the physician should be contacted. Consideration may be given to a slow flush of the CVC with normal saline.
Possible adverse effects include: tiredness, headaches, dizziness, nausea, light-headedness.
Possible drug interaction with metronidazole. Monitor for flushing, palpitations, tachycardia, nausea, vomiting.
Ethanol may disrupt the integrity of polyurethane catheters (eg. Bard-Poly-Per-Q). Ethanol lock is recommended only with silicone catheters.
For Methanol and Ethylene Glycol poisoning, see Ethanol 99%.
References
8, 126, 159
Last Edited
2019-01-24 17:36:24