FLUDROCORTISONE
(Florinef)Standard Prescription
fludrocortisone__mg PO [frequency]
Dosages
Infants and children:
Adults:
0.05-0.2 mg/dose PO daily
Adrenal Insufficiency: 0.05-0.1 mg/dose PO once or twice daily (Daily dose 0.05-0.2 mg)
Congenital adrenal hyperplasia (salt losers): 0.05-0.1 mg/dose PO once or twice daily (Usual daily dose 0.05-0.2 mg/day; however, doses as high as 0.3 mg per day may be required) .
Adults:
0.05-0.2 mg/dose PO daily
Mechanism of Action
Synthetic mineralocorticoid
Forms Supplied
tablet: 0.1 mg
Comments
Tablets may be crushed and placed in 1 tsp water or soft food (ex. yogurt, applesauce).
Titrate dose to maintain plasma renin activity at normal levels.
Monitor BP, serum electrolytes and glucose. Adjust dose if hypertension, hypernatremia or hypokalemia develop.
Has primarily mineralocorticoid activity.
Refer to Corticosteroid Equivalency Table in Supplementary Materials.
Contraindicated in systemic fungal infections.
Use with caution in heart failure, hypertension, edema, diabetes, renal or liver dysfunction, GI disorders.
References
44
Last Edited
2021-12-07 20:44:06