GROWTH HORMONE

(somatropin, Humatrope, Nutropin, Nutropin AQ, Saizen, Omnitrope, Genotropin)

Standard Prescription

Specify brand when ordering.

Humatrope__mg SC daily (__mg/kg/week)
Nutropin__mg SC daily (__mg/kg/week)
Nutropin AQ__mg SC daily (__mg/kg/week)
Saizen__mg SC daily (__mg/kg/week)
Omnitrope__mg SC daily (__mg/kg/week)
Genotropin__mg SC daily (__mg/kg/week)

Dosages

Growth Hormone Deficiency:
0.18-0.3 mg/kg/week SC in 6-7 divided doses.

Growth Hormone Deficiency in Patient Having Achieved Adult Height:
Initial dose: 0.005 mg/kg/day SC. Increase according to individual patient requirements to a maximum of 0.01 mg/kg/day.

Turner Syndrome:
0.3-0.375 mg/kg/week SC in 6-7 divided doses.

Idiopathic Short Stature:
0.3-0.375 mg/kg/week SC daily divided into 6-7 daily injections per week.

Small for Gestational Age:
0.3-0.375 mg/kg/week SC daily divided into 6-7 daily injections per week.

Prader-Willi Syndrome:
0.5-1 mg/m²/day SC daily divided into 6-7 daily injections per week.

Growth Failure due to Chronic Kidney Disease:
0.35 mg/kg/week SC in 6-7 divided doses.

Mechanism of Action

Growth hormone supplement

Forms Supplied

Humatrope: vials: cartridges for pens: 6 mg, 12 mg, 24 mg

Nutropin AQ: cartridges for NuSpin pens: 5 mg, 10 mg and 20 mg

Saizen: vials: 5 mg; cartridges for EasyPod device: 6 mg, 12 mg, 20 mg

Omnitrope: cartridges for pens: 5 mg, 10 mg, 15 mg

Genotropin:  cartridges for GoQuick pens: 5.3 mg, 12 mg

GoMini pre-dosed syringes: 0.6 mg, 0.8 mg, 1.0 mg, 1.2 mg, 1.4 mg, 1.6 mg, 1.8 mg, 2.0 mg

Norditropin: cartridges for Nordiflex pen: 5 mg, 10 mg, 15 mg

Comments

Somatropin is produced by a recombinant DNA process and has the same amino acid sequence as pituitary-derived somatropin.

Specify brand when ordering.

Clarify dose with Endocrinologist or Endocrine Clinic Nurse. Check with Nephrology for patient with chronic kidney disease (CKD)

BC PharmaCare ONLY reimburses GH for use in GH deficiency in children and growth failure due to CKD.

IGF-1 levels are used for titratring GH.

Pediatric Endocrinologists or Nephrologists should be consulted prior to considering hGH treatment.

References

4, 32, 44, 207








Last Edited

2022-01-05 07:47:11