IPRATROPIUM

(Atrovent)

Standard Prescription

ipratropium inhaler:__ puffs INH Q__H

ipratropium__mL (__mcg) INH via nebulizer Q__H

Dosages

Asthma Exacerbation (see Emergency Dept. protocol):
Metered Dose Inhaler (MDI):
3 puffs (<20kg) or 6 puffs (>=20kg) Q20 minutes x 3 doses in first hour, then stop.

Respiratory Solution:
0.25 mg (<20 kg) or 0.5 mg (>20 kg) Q20 minutes x 3 doses in first hour, then stop.

Mechanism of Action

Anticholinergic, Bronchodilator

Forms Supplied

respiratory solution: 0.025% (250 mcg/mL): 1 mL amps
inhaler: 20 mcg/puff

Comments

Onset of action: within 15 minutes.

Duration of effect: 2-6 hours.

MDI use with valved holding chamber (e.g. Aerochamber) recommended.

Respiratory solution may be mixed with salbutamol in mask prior to treatment for acute asthma.

Dilute respiratory solution with NS to a total volume of 4 mL and administer via nebulizer.

Inhaled anticholinergics are not recommended for long-term management of asthma in children due to lack of benefit.

Anticholinergic side effects:dry mouth, blurred vision, anxiety, GI discomfort

References

44, 127, 272, 273, 276, 277

Last Edited

2022-07-03 18:47:05