PROPRANOLOL
(Inderal, Hemangiol)Standard Prescription
propranolol __mg PO Q__H (__mg/kg/24 hr)
propranolol __mg IV x 1; may repeat Q__H prn (__mg/kg/dose)
propranolol __mg IV x 1; may repeat Q__H prn (__mg/kg/dose)
Dosages
Arrhythmias oral dosing:
Hypertension:
Initial 0.25-0.5 mg /kg/dose PO Q6-8H Usual range: 2-4 mg/kg/24hr PO div. Q68H.
Maximum: 16 mg/kg/24hr
Hypertension:
PO: 0.5-1 mg/kg/24 hr div. Q6-12H.
Maximum: 4 mg/kg/24 hr (Max 640 mg/24 hr)
Mechanism of Action
Non-selective beta-adrenergic receptor blocker.
Forms Supplied
tablet: 10 mg, 40 mg
liquid (BCCH): 2 mg/mL, 3.75 mg/mL
injection: 1 mg/mL
liquid (BCCH): 2 mg/mL, 3.75 mg/mL
injection: 1 mg/mL
Comments
Use caution in asthma (reactive airway disease).
Higher incidence of CNS effects (insomnia, lethargy) compared to other beta blockers.
May cause bradycardia, AV bloc.
Maximum dose of 16 mg/kg/24 may be exceeded with cardiology consult.
Esmolol is preferred for IV therapy.
Higher incidence of CNS effects (insomnia, lethargy) compared to other beta blockers.
May cause bradycardia, AV bloc.
Maximum dose of 16 mg/kg/24 may be exceeded with cardiology consult.
Esmolol is preferred for IV therapy.
References
29, 66, 141, 192
Last Edited
2022-09-08 05:28:17