LEVOCARNITINE
(l-carnitine, Carnitor)Standard Prescription
levocarnitine__mg PO Q__H (__mg/kg/24hr)
levocarnitine__mg IV x 1 dose (__mg/kg/dose)
levocarnitine__mg IV Q__H (__mg/kg/24hr)
levocarnitine__mg/kg/hr continuous IV infusion
levocarnitine__mg IV x 1 dose (__mg/kg/dose)
levocarnitine__mg IV Q__H (__mg/kg/24hr)
levocarnitine__mg/kg/hr continuous IV infusion
Dosages
IV:
Oral:
Doses up to 800 mg/kg/24 hr PO may be required in patients with excessive urinary loss.
50 mg/kg/dose IV bolus or infusion.
This may be followed by 50 mg/kg/dose by continuous infusion or div. Q4-6H. Maximum: 300 mg/kg/24 hr IV.
Oral:
16.7-33.3 mg/kg/dose PO Q8H.
Increase slowly to a maximum of 3 g/24 hr, if needed.
Doses up to 800 mg/kg/24 hr PO may be required in patients with excessive urinary loss.
Mechanism of Action
Amino acid
Forms Supplied
oral solution: 100 mg/mL
tablet: 330 mg
injection: 200 mg/mL
tablet: 330 mg
injection: 200 mg/mL
Comments
Used for the treatment of carnitine deficiency due to inborn error of metabolism, end stage renal disease, valproate toxicity, and cardiomyopathy.
Oral doses should be given with or following meals to maximize tolerability.
Oral solution may be mixed in drinks or other liquid food.
Oral doses should be given with or following meals to maximize tolerability.
Oral solution may be mixed in drinks or other liquid food.
May cause nausea, vomiting, abdominal cramps, diarrhea, body odor.
References
44
Last Edited
2019-04-09 04:02:49