LINEZOLID
(Zyvoxam)Standard Prescription
linezolid__mg IV/PO Q__H (__mg/kg/24hr)
Dosages
Children < 12 years:
10 mg/kg/dose PO/IV Q8H
> 12 years old and Adults:
10 mg/kg/dose PO/IV Q12H
Maximum: 600 mg/dose
10 mg/kg/dose PO/IV Q8H
> 12 years old and Adults:
10 mg/kg/dose PO/IV Q12H
Maximum: 600 mg/dose
Mechanism of Action
Oxazolidinone antibiotic: inhibits bacterial protein synthesis to prevent formation of 70S initiation complex
Forms Supplied
injection: 2 mg/mL (300 mL)
tablet: 600 mg
tablet: 600 mg
Comments
Bioavailability 100%
Reversible, nonselective MAO inhibitor. Check for drug interactions
Thrombocytopenia, anemia, leucopenia, pancytopenia reported with duration of therapy > 10 days. Monitoring CBC weekly during long-term therapy is recommended.
Reversible, nonselective MAO inhibitor. Check for drug interactions
Thrombocytopenia, anemia, leucopenia, pancytopenia reported with duration of therapy > 10 days. Monitoring CBC weekly during long-term therapy is recommended.
References
6, 44, 211
Last Edited
2022-07-05 21:15:03