SCOPOLAMINE HYDROBROMIDE
(Hyoscine)Standard Prescription
scopolamine __mcg SC/IM/IV/PO Q__H {PRN} (__mcg/kg/dose)
Dosages
Pre-op and antiemetic:
Children: 6 mcg/kg/dose SC/IM/IV/PO (max 0.3 mg/dose).
May repeat every 6-8 H.
Excessive drooling:
3-11 yrs: 1/2 patch applied transdermally Q72H.
>=12 yrs: 1 patch applied transdermally Q72H.
Children: 6 mcg/kg/dose SC/IM/IV/PO (max 0.3 mg/dose).
May repeat every 6-8 H.
Excessive drooling:
3-11 yrs: 1/2 patch applied transdermally Q72H.
>=12 yrs: 1 patch applied transdermally Q72H.
Mechanism of Action
Anticholinergic agent.
Forms Supplied
injection: 0.4 mg/mL, 0.6 mg/mL.
patch: 1.5 mg (non-formulary).
patch: 1.5 mg (non-formulary).
Comments
Contraindicated in patients with glaucoma, urinary or GI obstruction.
Well absorbed orally; peak concentration achieved in one hour.
Injectable form may be given orally.
Anticholinergic toxicities; see atropine comments. Case reports of toxicity with scopolamine patch. Monitor for hyperthermia, decreased vision, delirium. Use lowest effective dose.
Do not cut scopolamine patches. If a half patch is required, place Tegaderm or similar impermeable material on the skin underneath the patch, covering half the skin under the patch.
Well absorbed orally; peak concentration achieved in one hour.
Injectable form may be given orally.
Anticholinergic toxicities; see atropine comments. Case reports of toxicity with scopolamine patch. Monitor for hyperthermia, decreased vision, delirium. Use lowest effective dose.
Do not cut scopolamine patches. If a half patch is required, place Tegaderm or similar impermeable material on the skin underneath the patch, covering half the skin under the patch.
References
24, 44, 472, 473
Last Edited
2019-08-26 04:58:36