DEXTRAN 40

(Gentran)

Standard Prescription

Dextran 40 10% __ ml IV over __ mins (__ ml/kg)

Dosages

Pediatrics:
Infuse 1 g/kg/24 hour (Max: 2 g/kg/day for first 24 hours then 1 g/kg/day thereafter).
(1 g = 10 mL of 10% solution)

Mechanism of Action

Dextran is a complex branched glucan (polysaccharide) and provides an osmotically neutral fluid.

Forms Supplied

Injection: 10% Dextran 40 in D5W (500 mL bag)

Comments

Plasma volume expander

Maximum 5 days of therapy.

Risk of anaphylactic/anaphylactoid reaction.

References

44

Last Edited

2019-01-22 04:30:11