DEXTROSE, CONCENTRATED
(Glucose)Standard Prescription
Hypoglycemia:
Dextrose __ % __ g IV over __ minutes (__ g/kg).
Hyperkalaemia:
Dextrose 10% 0.5 g/kg (5 ml/kg) mixed with regular insulin 0.1 units/kg IV over __ minutes.
Dosages
Children < 50 kg:
Emergency treatment of hypoglycemia:
0.2-1 grams/kg/dose IV using dextrose 10-25%Non-emergent hypoglycemia:
0.2-3 grams/kg/dose using dextrose 10%
Hyperkalemia:
0.5 grams/kg/dose (5 mL/kg/dose) IV of dextrose 10% (maximum 25 grams/dose) over 30 mintues (mixed with regular insulin 0.1 units/kg/dose IV; maximum 10 units/dose)
Children > 50 kg:
Emergency treatment of hypoglycaemia:
12.5-25 grams/dose IV using dextrose 25%; may repeat Hyperkalemia:
25 grams/dose (250 mL of dextrose 10%) IV over 30 minutes (mixed with regular insulin 10 units/dose IV)
Mechanism of Action
Increases blood sugar
Forms Supplied
Injection: 50% PFS 50 mL, 10% bag
Comments
Dextrose 50% PFS must be diluted prior to infusion by peripheral vein.
Dextrose concentrations of 10% and higher are hypertonic. Infusion via peripheral vein may cause thrombophlebitis.
Extravasation injury may cause pain and local tissue necrosis.
Rapid administration may produce hyperglycemia, glucosuria, and electrolyte shifts.
Dextrose solutions may cause significant hyponatremia and water intoxication when infused in the absence of adequate sodium chloride.
Possible adverse effects include thrombophlebitis, pain, irritation at injection site.
Refer to Parenteral Manual for more information.
Dextrose concentrations of 10% and higher are hypertonic. Infusion via peripheral vein may cause thrombophlebitis.
Extravasation injury may cause pain and local tissue necrosis.
Rapid administration may produce hyperglycemia, glucosuria, and electrolyte shifts.
Dextrose solutions may cause significant hyponatremia and water intoxication when infused in the absence of adequate sodium chloride.
Possible adverse effects include thrombophlebitis, pain, irritation at injection site.
Refer to Parenteral Manual for more information.
References
37, 44, 205
Last Edited
2019-01-23 06:28:56