MONTELUKAST
(Singulair)Standard Prescription
Montelucast __mg PO daily HS
Dosages
Children < 6 years old:
4 mg PO QHS
Children 6-14 years old:
5 mg PO QHS
Adults and Children >= 15 years old:
10 mg PO QHS
Mechanism of Action
Non-steriodal leukotriene receptor antagonist
Forms Supplied
oral granules: 4 mg (not stocked at BCCH)
chewable tablets: 4 mg, 5 mg
chewable tablets: 4 mg, 5 mg
tablets: 10 mg
Comments
May be used as adjunctive therapy with moderate to high doses of inhaled corticosteroids.
May have steroid-sparing properties; allowing for better asthma control at a reduced dose of inhaled corticosteroids.
Metabolized extensively by CYP 3A4, 2C8, 2C9
Side effects: headache, flu-like symptoms, abdominal pain, cough.
Neuropsychiatric events (abnormal dreams, hallucinations, suicide ideation/behavior, tremors) and development of Churg-Strauss syndrome have been reported in a few case reports.
May have steroid-sparing properties; allowing for better asthma control at a reduced dose of inhaled corticosteroids.
Metabolized extensively by CYP 3A4, 2C8, 2C9
Side effects: headache, flu-like symptoms, abdominal pain, cough.
Neuropsychiatric events (abnormal dreams, hallucinations, suicide ideation/behavior, tremors) and development of Churg-Strauss syndrome have been reported in a few case reports.
References
44, 127, 275
Last Edited
2022-07-06 20:24:40