BUDESONIDE
(Pulmicort)Standard Prescription
budesonide (turbuhaler) __mcg inhaled Q H (__mcg/24hr)
budesonide (respiratory Solution) __mg nebulized Q H (__mg/24hr)
budesonide (respiratory Solution) __mg nebulized Q H (__mg/24hr)
Dosages
Turbuhaler:
Low dose:
100-200 mcg/dose inhaled BID
Medium dose:
>200-400 mcg/dose inhaled BID
High dose:
>400-800 mcg/dose inhaled BID
Respiratory Solution:
Low dose:
0.125-0.25 mg/dose inhaled BID
Medium dose:
>0.25-0.5 mg/dose inhaled BID
High dose:
>0.5-1 mg/dose inhaled BID
Mechanism of Action
Inhaled corticosteroid
Forms Supplied
"Turbuhaler" inhaler:
100 mcg/inhalation, 200 mcg/inhalation
(400 mcg/inhalation turbuhaler is non-formulary at BCCH)
Respiratory solution:
0.25 mg/mL - 2 mL nebule
0.5 mg/mL - 2 mL nebule
100 mcg/inhalation, 200 mcg/inhalation
(400 mcg/inhalation turbuhaler is non-formulary at BCCH)
Respiratory solution:
0.25 mg/mL - 2 mL nebule
0.5 mg/mL - 2 mL nebule
Comments
Not available as MDI (metered dose inhaler) puffer. Refer to fluticasone, ciclesonide, or beclomethasone monograph for inhaled steroid MDI dosing.
Significant improvements may be seen within 4-7 days.
Doses for different administration methods (nebulizer vs turbuhaler) are not interchangeable
Dose depends upon severity and response. Titrate to lowest effective dose.
High dose may be associated with significant side effects → refer to asthma specialist.
Side effects: dysphonia and oral thrush. Rinse mouth after inhalation.
100 mcg ciclesonide= 125 mcg fluticasone = 100 mcg beclomethasone dipropionate = 200 mcg budesonide
Health Canada approved age of use for Turbuhaler is >6 years old.
May dilute respiratory solution in 2-4 mL of NS and administer via nebulizer. May be mixed with salbutamol respiratory solution.
References
44, 127, 189, 198
Last Edited
2022-06-08 22:42:49