BUMETANIDE

(Burinex)

Standard Prescription

bumetanide __mg (__mg/kg/dose) (PO/NG/IV) Q__H

Dosages

Infants and children:
0.015 to 0.1 mg/kg/dose PO/NG/IV every 6 to 24 hrs

Adults:
0.5 to 2 mg/dose PO/NG/IV every 12 to 24 hrs; Maximum 10 mg/day

Mechanism of Action

Loop diuretic

Forms Supplied

Tablet: 1 mg, 5 mg

Injection: 2 mg/4 mL
(injection requires approval from Health Canada Special Access Program)

Comments

May cause hypokalemia, alkalosis, dehydration, hyperuricemia, increased calcium and magnesium excretion, nephrocalcinosis.

For use in cardiac patients who are unresponsive to furosemide.

Maximal diuretic effects were found to occur at doses of 0.04 mg/kg in critically ill infants.

References

44, 112

Last Edited

2018-12-03 04:36:14