CALCITRIOL
(Rocaltrol, 1,25-dihydroxycholecalciferol, Calcijex injection)Standard Prescription
calcitriol __mcg PO __ daily
calcitriol __mcg IV __(frequency)
calcitriol __mcg IV __(frequency)
Dosages
Secondary hyperparathyroidism in CKD:
>= 3 years: 0.25 to 0.5 mcg once daily
(Maximum 1 mcg/day)
0.25 - 0.5 micrograms IV 3 x weekly. Titrate by 0.25-0.5 mcg Q2-4 weeks as necessary to a maximum of 4 mcg 3 x weekly.
Mechanism of Action
Vitamin D analog
Forms Supplied
capsule: 0.25 mcg, 0.5 mcg
Comments
Dose adjustment based on serum iPTH. Usual maximum doses may be exceeded in consultation with nephrology or endocrinology
Monitor calcium, phosphate, iPTH, magnesium, alkaline phosphatase frequently until dose is stabilized.
Injectable may be used ORALLY. If liquid withdrawn from ampoule for storage in PO syringe prior to use, requires protection from light (wrap syringe in foil).
There are various dosing schedules depending on indication and further references should be consulted.
Does not require renal or hepatic activation.
Avoid oral use with mineral oil.
Monitor calcium, phosphate, iPTH, magnesium, alkaline phosphatase frequently until dose is stabilized.
Injectable may be used ORALLY. If liquid withdrawn from ampoule for storage in PO syringe prior to use, requires protection from light (wrap syringe in foil).
There are various dosing schedules depending on indication and further references should be consulted.
Does not require renal or hepatic activation.
Avoid oral use with mineral oil.
References
1, 32, 44
Last Edited
2022-06-16 03:46:25