CALCIUM GLUCONATE
Standard Prescription
calcium gluconate mg IV ( mg/kg/dose) x 1 dose
calcium gluconate mg/hr IV infusion (__mg/kg/hr)
calcium gluconate mg/hr IV infusion (__mg/kg/hr)
Dosages
Hypocalcemia, Hypermagnesemia or Calcium Channel Blocker Overdose:
0.6 mL-1 mL /kg/dose (5.6-9.3 mg elemental Ca/kg/dose [60-100 mg Ca gluconate/kg/dose]) IV push. Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose)
Hyperkalemia
0.5 mL/kg/dose (4.6 mg elemental Ca/kg/dose [50 mg Ca gluconate/kg/dose]) IV push. Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose). May repeat dose in 5 minutes if ECG changes persist
Hypocalcemia with seizures or tetany
1 mL/kg/dose (9.3 mg elemental Ca/kg/dose [100 mg Ca gluconate/kg/dose]) IV push, may repeat in 6 hours or continue with an infusion 18.6 mg elemental Ca/kg/day (200 mg Ca gluconate/kg/24h)
Continuous IV infusion:
18.6-47 mg elemental Ca/kg/24 hr
(200-500 mg Ca gluconate/kg/24 hr)
0.6 mL-1 mL /kg/dose (5.6-9.3 mg elemental Ca/kg/dose [60-100 mg Ca gluconate/kg/dose]) IV push. Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose)
Hyperkalemia
0.5 mL/kg/dose (4.6 mg elemental Ca/kg/dose [50 mg Ca gluconate/kg/dose]) IV push. Max 279 mg elemental Ca/dose (3000 mg Ca gluconate/dose). May repeat dose in 5 minutes if ECG changes persist
Hypocalcemia with seizures or tetany
1 mL/kg/dose (9.3 mg elemental Ca/kg/dose [100 mg Ca gluconate/kg/dose]) IV push, may repeat in 6 hours or continue with an infusion 18.6 mg elemental Ca/kg/day (200 mg Ca gluconate/kg/24h)
Continuous IV infusion:
18.6-47 mg elemental Ca/kg/24 hr
(200-500 mg Ca gluconate/kg/24 hr)
Mechanism of Action
Calcium electrolyte replacement
Forms Supplied
injection: 10% (100 mg/mL) 10 mL vial
10% solution contains: 0.23 mmol elemental Ca/mL, 9.3 mg elemental Ca/mL
Comments
1 gram calcium gluconate = 93 mg elemental calcium (Ca) = 2.3 mmol elemental Ca.
Routine use in cardiac arrest is not recommended due to lack of survival benefit.
Calcium chloride is preferred to correct emergent hypocalcemia.
Contraindicated in patients with digoxin toxicity or hypercalcemia.
Incompatible with sodium bicarbonate, ceftriaxone, phosphate, and lipids.
Monitor for bradycardia or dysrhythmia.
Avoid extravasation as severe necrosis and tissue sloughing will occur.
Refer to ePOPS for Prevention and Management of Infiltration and Extravasation Calcium concentration should be less than 20 mg/mL for peripheral administration.
Routine use in cardiac arrest is not recommended due to lack of survival benefit.
Calcium chloride is preferred to correct emergent hypocalcemia.
Contraindicated in patients with digoxin toxicity or hypercalcemia.
Incompatible with sodium bicarbonate, ceftriaxone, phosphate, and lipids.
Monitor for bradycardia or dysrhythmia.
Avoid extravasation as severe necrosis and tissue sloughing will occur.
Refer to ePOPS for Prevention and Management of Infiltration and Extravasation Calcium concentration should be less than 20 mg/mL for peripheral administration.
References
37, 44
Last Edited
2021-11-13 04:51:33