CEPHALEXIN
(Keflex)Standard Prescription
cephalexin__mg PO Q__H (__mg/kg/24hr)
Dosages
Children:
Mild to Moderate Infections:
15 mg/kg/dose PO Q8H or Q6H. Max 4 g/day
Severe Infections:
25 mg/kg/dose PO Q6H. Max 4 g/day
Osteomyelitis:
37.5 mg/kg/dose PO Q6H. Max 4 g/day
Cystic Fibrosis:
Adults:
Mild to Moderate infections:
250-500 mg/dose PO Q6H. Max 4 g/day
Severe Infections:
500-1000 mg/dose PO Q6H. Max 4 g/day
Mild to Moderate Infections:
15 mg/kg/dose PO Q8H or Q6H. Max 4 g/day
Severe Infections:
25 mg/kg/dose PO Q6H. Max 4 g/day
Osteomyelitis:
37.5 mg/kg/dose PO Q6H. Max 4 g/day
Cystic Fibrosis:
25-40 mg/kg/dose PO Q6H. Max 4 g/day
Mild to Moderate infections:
250-500 mg/dose PO Q6H. Max 4 g/day
Severe Infections:
500-1000 mg/dose PO Q6H. Max 4 g/day
Mechanism of Action
First generation cephalosporin antibiotic
Forms Supplied
Capsule: 250 mg, 500 mg
Suspension: 50 mg/mL
Suspension: 50 mg/mL
Comments
More palatable, less GI upset and higher bioavailability than PO cloxacillin.
Cefazolin sensitivity does not predict susceptibility to cephalexin.
Dosage adjustment required in renal impairment.
Cefazolin sensitivity does not predict susceptibility to cephalexin.
Dosage adjustment required in renal impairment.
References
44, 614
Last Edited
2022-06-16 00:24:53