PREFACE TO THE 9th EDITION
The 9th edition of the BC Children's Hospital Pediatric Drug Dosage Guidelines is updated and revised thanks to the many pharmacists and physicians who contributed their time and expertise. Many new monographs have been added and several have been deleted, due either to obsolescence or unavailability. Changes with this new edition include the implementation of a new style guide and improvements to language.
The drug monographs and practice recommendations contained in this book reflect the current practices at BC Children's Hospital. Drug information evolves constantly as a result of ongoing research and clinical experience. It is subject to interpretation. Every effort has been made to ensure the accuracy of drug dosages and associated information. It is the responsibility of the prescriber to evaluate the appropriateness of a particular recommendation in each situation. The information and dosage guidelines reflect the general practice guidelines at BCCH, which is a tertiary care and teaching hospital, and may not be suitable for all settings in which children may be treated. This book is intended as a quick reference for healthcare providers familiar with pediatric treatment. Other references should be consulted for those who are unfamiliar with the drug or disease. The authors, editors, reviewers, contributors and publishers cannot be responsible for the continued currency of the information or for any errors, omissions or for how this information is applied to individual patients.
Most of the content of this book can be found on the PHSA POD. Updates to monographs and guidelines following publication of the print edition will be found here.
The editor wishes to thank all the pharmacists and physicians who wrote, revised, reviewed or otherwise contributed to this 8th edition; their time and knowledge is greatly appreciated.
The dosing handbook was started in 1993 with a grant from the Children's Miracle Network Telethon and has been more or less self-sustaining ever since. Ms. Roberta Esau served as editor until 2018, with the publication of the 7th edition. We would like to thank her for her significant contributions.
Dr. Jennifer Kendrick, Editor
Dr. Ran Goldman, Chairperson, Pharmacy, Therapeutics and Nutrition Committee.
Previous Editions:
First Edition: 1993
Second Edition: 1995/96
Third Edition: 1999/2000
Fourth Edition: 2002/2003
Fifth Edition: 2006/2007
Sixth Edition: 2011
Sixth Edition, 2nd printing: 2013
Seventh Edition: 2018
Seventh Edition, 2nd printing: 2019
Eighth Edition: 2022
Ninth Edition: 2025
Copyright 2025 by the Department of Pharmacy
Children's & Women's Health Centre of British Columbia
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior written permission of:
Department of Pharmacy
Children's & Women's Health Centre of British Columbia
4480 Oak Street
Vancouver, B.C. V6H 3V4
ACKNOWLEDGMENTS:
The following individuals provided valuable assistance in the preparation and review of this publication. Their input is gratefully acknowledged.| Pharmacists | |
|---|---|
| Ms. Mattie Bakker | Dr. Laura Beresford |
| Ms. Iona Berger | Dr. Roxane Carr |
| Ms. Eva Cho | Dr. Dean Elbe |
| Dr. Juliana Gotha | Dr. Katie Haubrich |
| Ms. Sonia Jeffries | Dr. Jennifer Kendrick |
| Dr. Natasha Kwan | Dr. Julia Lamb |
| Ms. Maggie Lee | Ms. Sarah Leung |
| Dr. Kate McDougal | Ms. Karen Ng |
| Ms. Charmaine Ngo | Dr. Vanessa Paquette |
| Ms. Laura Rozka | Ms. Joanie Shew |
| Dr. Kendra Sih | Dr. Jason Tan | Dr. Stacey Tkachuk | Mr. Kelvin Won |
| Medical Staff | |
| Dr. Mark Belletrutti | Dr. Tom Blydt-Hansen |
| Dr. Sonia Butterworth | Dr. Linda Casey |
| Dr. Julia Charlton | Dr. Mark Chilvers |
| Dr. Jake Cosme | Dr. Michael Correia |
| Dr. Sharon Dell | Dr. Jen Ernst |
| Dr. Meg Gilley | Dr. Jess Halparin |
| Dr. Kristin Houghton | Dr. Martin Hosking |
| Dr. Linda Huh | Dr. Drew Huang |
| Dr. Sally Hynes | Dr. Sally Lawrence |
| Dr. Joseph Lam | Dr. Grce Li |
| Dr. Andrew MacNeily | Dr. Cherry Mammen |
| Dr. Mina Matsuda-Abedini | Dr. Alistair McAlpine |
| Dr. Garth Meckler | Dr. Dan Metzger |
| Dr. Ram Mishaal | Dr. Srin Murthy |
| Dr. Simone Nicol | Dr. Horacio Osiovich |
| Dr. John Ramsey | Dr. Jacob Rozmus | Dr. Ramona Salvarinova | Dr. Shu Sanatani |
| Dr. Blake Sandary | Dr. Kelly Saran |
| Dr. Laura Sauve | Dr. Kathy Selby |
| Dr. Erik Skarsgard | Dr. Caron Strahlendorf |
| Dr. Nicole Todd | Dr. Mumtaz Virji |
| Dr. Scott Wenderfer | Dr. Simon Whyte |
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